Title : COX-2 expression positively correlates with PD-L1 expression in human melanoma cells.

Pub. Date : 2017 Feb 23

PMID : 28231855






2 Functional Relationships(s)
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1 Lastly the BRAFV600E A375 and NRASQ61R SK-MEL-2 melanoma cell lines were used to evaluate the effect of COX-2 inhibition by celecoxib on expression of PD-L1 in vitro. Celecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 Lastly, inhibition of COX-2 activity by celecoxib down-regulated the expression of PD-L1 in both BRAFV600E A375 and NRASQ61R SK-MEL-2 melanoma cell lines. Celecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens