Title : Acetylenic nucleosides. 4. 1-beta-D-arabinofuranosyl-5-ethynylcytosine. Improved synthesis and evaluation of biochemical and antiviral properties.

Pub. Date : 1987 Nov

PMID : 2822932






1 Functional Relationships(s)
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1 EAC also showed activity against a strain of HSV-1 resistant to (E)-5-(2-bromovinyl)-2"-deoxyuridine which has an alteration of the virus-induced thymidine kinase (TK). brivudine involved in nucleotide metabolism Human alphaherpesvirus 1