Title : Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.

Pub. Date : 2017 Mar 15

PMID : 28221788






2 Functional Relationships(s)
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1 Substituted 2-Aminopyrimidines Selective for alpha7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins. 2-aminopyrimidine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens
2 Initial screening of a series of over 50 newly characterized 2-aminopyrimidines with affinity for AChBP showed only two to be agonists on the alpha7-nAChR below 10 muM concentration. 2-aminopyrimidine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens