Title : Deconstructed Analogues of Bupropion Reveal Structural Requirements for Transporter Inhibition versus Substrate-Induced Neurotransmitter Release.

Pub. Date : 2017 Jun 21

PMID : 28220701






2 Functional Relationships(s)
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Protein Name
Organism
1 Bulky amine substituents resulted in compounds that function as DAT uptake inhibitors but not release agents, whereas smaller amine substituents result in relatively nonselective releasing agents at DAT and NET. Amines solute carrier family 6 member 3 Homo sapiens
2 Bulky amine substituents resulted in compounds that function as DAT uptake inhibitors but not release agents, whereas smaller amine substituents result in relatively nonselective releasing agents at DAT and NET. Amines solute carrier family 6 member 3 Homo sapiens