Title : ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population.

Pub. Date : 2017 Jul

PMID : 28220208






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ABCB4 flops phosphatidylcholine into the outer leaflet of the membrane to be extracted by bile salts in the canalicular space. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens