Title : Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.

Pub. Date : 2017 Mar 23

PMID : 28218845






1 Functional Relationships(s)
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1 Cellular potency was enhanced >600-fold in the tris-POM prodrug (EC50 = 0.041 muM). Tromethamine latexin Homo sapiens