Title : Protective effect of DHEA on hydrogen peroxide-induced oxidative damage and apoptosis in primary rat Leydig cells.

Pub. Date : 2017 Mar 7

PMID : 28212544






2 Functional Relationships(s)
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1 DHEA treatment decreased Bax, capase-9 and capase-3 mRNA levels in H2O2-treated Leydig cells. Hydrogen Peroxide BCL2 associated X, apoptosis regulator Rattus norvegicus
2 Meanwhile, pre-treatment with DHEA inhibited H2O2-induced Leydig cells early apoptosis which mainly by reducing the pro-apoptotic protein Bax and caspases-9, caspases-3 mRNA levels. Hydrogen Peroxide BCL2 associated X, apoptosis regulator Rattus norvegicus