Title : Sulfated glycosaminoglycans and non-classically secreted proteins, basic FGF and epimorphin, coordinately regulate TGF-β-induced cell behaviors of human scar dermal fibroblasts.

Pub. Date : 2017 May

PMID : 28209294






3 Functional Relationships(s)
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Protein Name
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1 RESULTS: A highly sulfated chondroitin sulfate (CS-E) or its substitute (heparinoid) had marked inhibitory effects on TGF-beta-mediated changes in HSF behaviors. Chondroitin Sulfates transforming growth factor beta 1 Homo sapiens
2 RESULTS: A highly sulfated chondroitin sulfate (CS-E) or its substitute (heparinoid) had marked inhibitory effects on TGF-beta-mediated changes in HSF behaviors. Chondroitin Sulfates transforming growth factor beta 1 Homo sapiens
3 CONCLUSIONS: TGF-beta, bFGF and epimorphin in the extracellular microenvironment cooperatively affect HSF behaviors under the control of a highly sulfated chondroitin sulfate. Chondroitin Sulfates transforming growth factor beta 1 Homo sapiens