Title : Inhibition of autophagy blocks cathepsins-tBid-mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes.

Pub. Date : 2017 Feb 16

PMID : 28206988






1 Functional Relationships(s)
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1 Immunofluorescence analysis showed that 3-MA or Wort treatment reversed OGD-induced release of cathepsin B and L from the lysosome to the cytoplasm and activation of caspase-3 in the astrocytes. 3-methyladenine caspase 3 Rattus norvegicus