Title : Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance.

Pub. Date : 2017 Feb 10

PMID : 28187790






1 Functional Relationships(s)
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1 Co-targeting of the retinoic acid and TGF-beta pathways, through RA and kartogenin (KGN; a TGF-beta signalling activating small molecule) combination treatment, induced the loss of viability of MYCN-amplified retinoid-resistant neuroblastoma cells. Tretinoin transforming growth factor beta 1 Homo sapiens