Pub. Date : 2018 Jan
PMID : 28179185
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mechanism of action of DS operates by way of cyclooxygenase (COX) inhibition. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | As a non-steroidal anti-inflammatory drug (NSAID), DS binds to both forms of COX (COX-1 and COX-2) and inhibits the conversion of arachidonic acid into pro-inflammatory prostaglandins by means of chelation. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | As a non-steroidal anti-inflammatory drug (NSAID), DS binds to both forms of COX (COX-1 and COX-2) and inhibits the conversion of arachidonic acid into pro-inflammatory prostaglandins by means of chelation. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 4 | DS is effective in overcoming pain and inflammation when it inhibits COX-2, but gastrointestinal side effects appear when it inhibits COX-1. | Diclofenac | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |