Title : Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol.

Pub. Date : 2008 Apr

PMID : 28178465






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The alpha-tocopherol was covalently bound to the antisense strand of 27/29-mer siRNA at the 5"-end (Toc-siRNA). alpha-Tocopherol rhomboid 5 homolog 2 Homo sapiens
2 The 27/29-mer Toc-siRNA was designed to be cleaved by Dicer, producing a mature form of 21/21-mer siRNA after releasing alpha-tocopherol. alpha-Tocopherol rhomboid 5 homolog 2 Homo sapiens