Pub. Date : 2017 Feb 21
PMID : 28167750
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection. | Acetyl Coenzyme A | acyl-CoA synthetase short chain family member 2 | Homo sapiens |
| 2 | In mammalian cells the central precursor for lipid biosynthesis, cytosolic acetyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mitochondria-derived citrate or by acetyl-CoA synthetase short-chain family member 2 (ACSS2) from acetate. | Acetyl Coenzyme A | acyl-CoA synthetase short chain family member 2 | Homo sapiens |
| 3 | In mammalian cells the central precursor for lipid biosynthesis, cytosolic acetyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mitochondria-derived citrate or by acetyl-CoA synthetase short-chain family member 2 (ACSS2) from acetate. | Acetyl Coenzyme A | acyl-CoA synthetase short chain family member 2 | Homo sapiens |
| 4 | This reduction suggests that glucose-derived acetate is being used to synthesize cytosolic Ac-CoA by ACSS2. | Acetyl Coenzyme A | acyl-CoA synthetase short chain family member 2 | Homo sapiens |