Title : JAK inhibition in inflammatory bowel disease.

Pub. Date : 2017 Jul

PMID : 28164724






2 Functional Relationships(s)
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1 Among them, Janus kinase (JAK) inhibitors seem to have the lead, since tofacitinib has received regulatory approval in 2012 for the treatment of rheumatoid arthritis, and also it has shown a favorable risk-benefit ratio in phase 3 studies for ulcerative colitis, both in anti-TNF naive and anti-TNF experienced patients. tofacitinib tumor necrosis factor Homo sapiens
2 Among them, Janus kinase (JAK) inhibitors seem to have the lead, since tofacitinib has received regulatory approval in 2012 for the treatment of rheumatoid arthritis, and also it has shown a favorable risk-benefit ratio in phase 3 studies for ulcerative colitis, both in anti-TNF naive and anti-TNF experienced patients. tofacitinib tumor necrosis factor Homo sapiens