Title : Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis.

Pub. Date : 2017 Mar 15

PMID : 28137749






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation when bound to Munc18-1, preventing binding to synaptobrevin-2 and SNAP-25 to form the ternary SNARE complex. Ethylmaleimide synaptosome associated protein 25 Homo sapiens