Pub. Date : 2017 Jan
PMID : 28133531
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Both of coumarin and ICE were capable to reduce the PGE2, TNF-alpha, NO, IL-6, and IL-beta level in LPS-induced RAW264.7 cells. | coumarin | tumor necrosis factor | Mus musculus |
| 2 | Coumarin had higher activity to decrease PGE2 and TNF-alpha, whilst ICE had higher activity to inhibit NO, IL-6, and IL-beta levels. | coumarin | tumor necrosis factor | Mus musculus |
| 3 | CONCLUSION: Coumarin and ICE possess anti-inflammatory properties through inhibition of PGE2 and NO along with pro-inflammatory cytokines TNF-alpha, IL-6, IL-1beta production. | coumarin | tumor necrosis factor | Mus musculus |