Title : PI3K-δ inhibition using CAL-101 exerts apoptotic effects and increases doxorubicin-induced cell death in pre-B-acute lymphoblastic leukemia cells.

Pub. Date : 2017 Apr

PMID : 28125433






1 Functional Relationships(s)
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1 CAL-101 also leads to induction of caspase-dependent apoptosis probably through reactive oxygen species-dependent upregulation of FOXO3a and subsequent induction of the proapoptotic target genes of p53. idelalisib tumor protein p53 Homo sapiens