Pub. Date : 2017 Jan 23
PMID : 28112722
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A computational model predicted that myeloperoxidase efficiently scavenges diffusible H2O2 at the surface of phagosomal Salmonella and converts it into highly reactive HOCl (bleach), which rapidly damages biomolecules within a radius of less than 0.1 mum. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
2 | These data show that myeloperoxidase has a major function in mitigating collateral tissue damage during antimicrobial oxidative bursts, by converting diffusible long-lived H2O2 into highly reactive, microbicidal and locally confined HOCl at pathogen surfaces. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |