Title : Downregulation of miR-382 by propranolol inhibits the progression of infantile hemangioma via the PTEN-mediated AKT/mTOR pathway.

Pub. Date : 2017 Mar

PMID : 28112362






3 Functional Relationships(s)
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1 Downregulation of miR-382 by propranolol inhibits the progression of infantile hemangioma via the PTEN-mediated AKT/mTOR pathway. Propranolol AKT serine/threonine kinase 1 Homo sapiens
2 The expression of PTEN was upregulated, while that of p-AKT, p-mTOR and p-p70S6K was downregulated by propranolol; these effects were partly reversed by the overexpression of miR-382. Propranolol AKT serine/threonine kinase 1 Homo sapiens
3 On the whole, our study identified that the downregulation of miR-382 by propranolol inhibits the progression of IHs via the PTEN-mediated AKT/mTOR pathway. Propranolol AKT serine/threonine kinase 1 Homo sapiens