Pub. Date : 2017 Mar
PMID : 28112362
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Downregulation of miR-382 by propranolol inhibits the progression of infantile hemangioma via the PTEN-mediated AKT/mTOR pathway. | Propranolol | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | The expression of PTEN was upregulated, while that of p-AKT, p-mTOR and p-p70S6K was downregulated by propranolol; these effects were partly reversed by the overexpression of miR-382. | Propranolol | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | On the whole, our study identified that the downregulation of miR-382 by propranolol inhibits the progression of IHs via the PTEN-mediated AKT/mTOR pathway. | Propranolol | AKT serine/threonine kinase 1 | Homo sapiens |