Pub. Date : 2017
PMID : 28103302
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells. | flavokawain B | uridine-cytidine kinase 2 | Homo sapiens |
2 | Initial results from in vitro studies have shown the ability of the bioactive compounds of flavokawain B and alpinetin to target UCK2 enzyme specifically, inducing cell cycle arrest and subsequently leading to cancer cell death, possibly through interfering the MDM2-p53 signalling pathway. | flavokawain B | uridine-cytidine kinase 2 | Homo sapiens |