Title : Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.

Pub. Date : 2017 Mar

PMID : 28092375






1 Functional Relationships(s)
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1 IL-1beta and insulin increased the uptake of glucose into macrophages, and insulin reinforced a pro-inflammatory pattern via the insulin receptor, glucose metabolism, production of reactive oxygen species, and secretion of IL-1beta mediated by the NLRP3 inflammasome. Reactive Oxygen Species interleukin 1 beta Mus musculus