Pub. Date : 1989 Nov 1
PMID : 2809211
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Peak SAP mRNA concentrations were observed 8 h after thioglycollate and 12 to 18 h after azocasein injection; by 36 h concentrations were close to preinflammatory levels. | Thioglycolates | amyloid P component, serum | Mus musculus |
| 2 | All mRNA species studied (SAP, SAA and the complement components C3, C5 and factor B) were induced more rapidly by the thioglycollate stimulus and reached higher peak concentrations. | Thioglycolates | amyloid P component, serum | Mus musculus |
| 3 | SAP mRNA levels were correlated with other parameters of inflammation: infiltration of peritoneal exudate cells (PEC) into the peritoneum after thioglycollate injection, and serum concentrations of SAP after azocasein injection. | Thioglycolates | amyloid P component, serum | Mus musculus |
| 4 | The highest numbers of PEC were present 24 h after the thioglycollate stimulus, i.e. 16 h after the maximum SAP mRNA concentration, indicating the continuation of an active local inflammation many hours after one aspect of the systemic response has ceased. | Thioglycolates | amyloid P component, serum | Mus musculus |