Title : Alterations in transcription and protein expressions of HCC-related genes in HepG2 cells caused by microcystin-LR.

Pub. Date : 2017 Apr

PMID : 28062358






1 Functional Relationships(s)
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1 The results of qPCR and Western blotting showed that MC-LR-exposure at non- or sub-cytotoxic concentrations promoted the expressions of oncogenes c-fos, c-jun, c-myc, c-met, and N-ras while suppressed tumor-suppressor gene PTEN in HepG2 cells at both transcription and protein levels. Lawrencium NRAS proto-oncogene, GTPase Homo sapiens