Title : Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.

Pub. Date : 2017 Aug

PMID : 28058446






1 Functional Relationships(s)
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1 Changes in the expression of classic CAR/PXR target genes such as Cyp2b10 were induced by cyproconazole and phenobarbital in both genotypes, while prochloraz treatment resulted in gene expression changes indicative of additional aryl hydrocarbon receptor activation, e.g. by up-regulation of Cyp1a1 expression. Phenobarbital nuclear receptor subfamily 1, group I, member 2 Mus musculus