Title : JNK activation is essential for activation of MEK/ERK signaling in IL-1β-induced COX-2 expression in synovial fibroblasts.

Pub. Date : 2017 Jan 5

PMID : 28054591






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These observations suggest that JNK1 phosphorylation is necessary for the activation of the MEK/ERK1/2 pathway and the subsequent COX-2 expression for PGE2 release, and p38 independently contributes to the IL-1beta effect in synovial fibroblasts. Dinoprostone mitogen-activated protein kinase 8 Homo sapiens