Title : Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin.

Pub. Date : 2017 Jan 31

PMID : 28052008






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Metformin tumor protein p53 Homo sapiens
2 Taken together, combination of metformin and 2-deoxyglucose reverses MDR of MCF-7/Dox cells by recovering p53 function and increasing doxorubicin accumulation. Metformin tumor protein p53 Homo sapiens