Pub. Date : 2017
PMID : 28044934
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Results & Conclusion: Studies on cells revealed that 2 (i) demonstrated a high antiproliferative effect, which was higher toward HeLa and C6 cancer cells than toward healthy Vero cells; (ii) impaired the migration of HeLa cells; (iii) altered the P53-Bcl-2 ratio in favor of apoptosis; (iv) strongly bound to DNA/BSA macromolecules; and (v) inhibited human topoisomerase I and KpnI or BamHI restriction endonucleases. | Adenosine Monophosphate | tumor protein p53 | Homo sapiens |