Title : ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.

Pub. Date : 2016

PMID : 28018360






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1 Our results showed that AMPK signaling was activated in murine macrophages upon ATP treatment, which was accompanied by inflammasome activation and pyroptosis as evidenced by rapid cell membrane rupture as well as mature interleukin (IL)-1beta and active caspase-1p10 release. Adenosine Triphosphate interleukin 1 beta Mus musculus