Pub. Date : 2017 Feb
PMID : 28013187
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To gain insight into the molecular mechanisms, we evaluated the effect of halofuginone on the MAPK and AKT pathways. | halofuginone | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Our results indicated that halofuginone inhibited the activity of MAPK and AKT. | halofuginone | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Taken together, these results suggest that halofuginone may protect against joint destruction in RA by regulating synoviocyte migration, invasion and cell proliferation by inhibiting MAPK and AKT activation. | halofuginone | AKT serine/threonine kinase 1 | Homo sapiens |