Pub. Date : 1989 Jun
PMID : 2801311
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitory effect of SK&F 86002 on monocyte IL-1 production. | amicloral | interleukin 1 alpha | Homo sapiens |
| 2 | SK&F 86002-A2 was shown to be a potent inhibitor of IL-1 production with a 50% inhibitory concentration (IC50) of 1.3 +/- 0.5 microM. | amicloral | interleukin 1 alpha | Homo sapiens |
| 3 | Thus, SK&F 86002 may serve as a useful reagent in the understanding of the synthetic, processing and/or secretory pathways of interleukin-1, and may provide important insight into the treatment of disease states where aberrant IL-1 production is implicated. | amicloral | interleukin 1 alpha | Homo sapiens |