Title : The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.

Pub. Date : 2017 Feb

PMID : 28003335






1 Functional Relationships(s)
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1 Moreover, a better response to EGFR-TKI was associated with low RHOB levels in a panel of lung tumor cell lines and in a lung-specific tetracycline-inducible EGFRL858R transgenic mouse model. Tetracycline epidermal growth factor receptor Homo sapiens