Title : SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.

Pub. Date : 2017 Feb

PMID : 27991919






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, dGTP-activated SAMHD1 hydrolyzes Ara-CTP, which results in a drastic reduction of Ara-CTP in leukemic cells. deoxyguanosine triphosphate SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens