Title : Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice.

Pub. Date : 2017 Feb

PMID : 27987210






1 Functional Relationships(s)
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1 The effect of fluvoxamine was blocked by a 5-HT1A or a sigma1 receptor antagonist, and co-administration of the sigma1 receptor agonist (+)-SKF-10047 and the 5-HT1A receptor agonist osemozotan mimicked the effect of fluvoxamine. Fluvoxamine 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus