Title : Irradiation with UV-C inhibits TNF-α-dependent activation of the NF-κB pathway in a mechanism potentially mediated by reactive oxygen species.

Pub. Date : 2017 Jan

PMID : 27976481






1 Functional Relationships(s)
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1 Accumulation of ROS and subsequent activation of NRF2, p53, AP-1 and NF-kappaB-dependent pathways, with downstream activation of antioxidant mechanisms (e.g., SOD2 and HMOX1 expression), is observed in the UV-treated cells. Reactive Oxygen Species tumor protein p53 Homo sapiens