Pub. Date : 2016 Dec
PMID : 27941164
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Single nucleotide polymorphisms of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) in Iranian patients with TB. | Terbium | interferon gamma | Homo sapiens |
| 2 | METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. | Terbium | interferon gamma | Homo sapiens |
| 3 | METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. | Terbium | interferon gamma | Homo sapiens |
| 4 | METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. | Terbium | interferon gamma | Homo sapiens |
| 5 | METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. | Terbium | interferon gamma | Homo sapiens |
| 6 | The serum level of IFNgamma was significantly higher in patients with TB than in controls, but there was no significant difference between serum level of IFNgamma and the studied genotypes (p>0.05). | Terbium | interferon gamma | Homo sapiens |
| 7 | CONCLUSIONS: The cause of active TB in the patients seems to be due to the lack of effective IFNgamma function or the lack of effective signaling connection between IFNgamma and its receptor in presence of -56 C/T polymorphism in promoter region of IFNgammaR1 gene. | Terbium | interferon gamma | Homo sapiens |