Title : Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor.

Pub. Date : 2017 Feb

PMID : 27934636






1 Functional Relationships(s)
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1 Only using the RAF derived from testosterone for CYP3A4 produced the expected CYP2C9 contribution of 72%-87% and 47%-69% for metabolism of losartan and meloxicam, respectively. Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens