Pub. Date : 2016 Nov 28
PMID : 27892461
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | ATP citrate lyase | Homo sapiens |
| 2 | Bempedoic acid (ETC-1002) is a small molecule intended to lower LDL-C in hypercholesterolemic patients, and has been previously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AMPK) activity in rodents. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | ATP citrate lyase | Homo sapiens |
| 3 | Bempedoic acid (ETC-1002) is a small molecule intended to lower LDL-C in hypercholesterolemic patients, and has been previously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AMPK) activity in rodents. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | ATP citrate lyase | Homo sapiens |
| 4 | Bempedoic acid (ETC-1002) is a small molecule intended to lower LDL-C in hypercholesterolemic patients, and has been previously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AMPK) activity in rodents. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | ATP citrate lyase | Homo sapiens |
| 5 | Bempedoic acid (ETC-1002) is a small molecule intended to lower LDL-C in hypercholesterolemic patients, and has been previously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AMPK) activity in rodents. | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid | ATP citrate lyase | Homo sapiens |