Title : CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma.

Pub. Date : 2016 Dec 27

PMID : 27888616






1 Functional Relationships(s)
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1 Finally, we reported that curcumin, a powerful natural drug, suppressed the production of EGF and CCL2 in macrophages and cancer cells, respectively, blocking the feedback loop and suppressing the migration and invasion of HNSCC cells. Curcumin C-C motif chemokine ligand 2 Homo sapiens