Pub. Date : 2016
PMID : 27885332
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results showed that THSG dose-dependently increased the luciferase reporter activity of the klotho gene, reversed the decrease in mRNA and protein expression of klotho which was induced by angiotensin II in NRK-52E renal tubular epithelial cells, and increased klotho mRNA expression in the cerebral cortex, hippocampus, testis, and kidney medulla of spontaneously hypertensive rats. | 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside | angiotensinogen | Rattus norvegicus |
| 2 | THSG also reduced the number of senescent cells induced by angiotensin II and improved the antioxidant capacity and enhanced the bone strength in vivo. | 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside | angiotensinogen | Rattus norvegicus |