Title : C-Peptide Levels Predict the Effectiveness of Dipeptidyl Peptidase-4 Inhibitor Therapy.

Pub. Date : 2016

PMID : 27882332






4 Functional Relationships(s)
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1 Our aim was to define the conditions that affect therapeutic success when dipeptidyl peptidase-4 (DPP-4) inhibitor is added to metformin monotherapy. Metformin dipeptidyl peptidase 4 Homo sapiens
2 Our aim was to define the conditions that affect therapeutic success when dipeptidyl peptidase-4 (DPP-4) inhibitor is added to metformin monotherapy. Metformin dipeptidyl peptidase 4 Homo sapiens
3 Patients who added DPP-4 inhibitor to metformin monotherapy had significant weight loss (P = 0.004) and FBG and HbA1c levels were significantly lowered during the first 6 months (both P < 0.001). Metformin dipeptidyl peptidase 4 Homo sapiens
4 Our study demonstrates that in patients having inadequate glycemic control, the addition of a DPP-4 inhibitor as a second oral agent to metformin monotherapy provides better glycemic control, protects beta-cell reserves, and does not cause weight gain. Metformin dipeptidyl peptidase 4 Homo sapiens