Title : Combining in silico and in vitro approaches to evaluate the acetylcholinesterase inhibitory profile of some commercially available flavonoids in the management of Alzheimer's disease.

Pub. Date : 2017 Feb

PMID : 27871793






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1 Combining in silico and in vitro approaches to evaluate the acetylcholinesterase inhibitory profile of some commercially available flavonoids in the management of Alzheimer"s disease. Flavonoids acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The current objective of the study is to identify inhibitory affinity potential of the certain commercially available flavonoids, against crystal structure of acetylcholinesterase (AChE) enzyme using in silico and in vitro studies. Flavonoids acetylcholinesterase (Cartwright blood group) Homo sapiens
3 The current objective of the study is to identify inhibitory affinity potential of the certain commercially available flavonoids, against crystal structure of acetylcholinesterase (AChE) enzyme using in silico and in vitro studies. Flavonoids acetylcholinesterase (Cartwright blood group) Homo sapiens
4 In vitro results showed that all the selected flavonoids displayed excellent concentration-dependant inhibition of AChE. Flavonoids acetylcholinesterase (Cartwright blood group) Homo sapiens