Title : Impact of gender on corticotropin-releasing factor and noradrenergic sensitivity in cocaine use disorder.

Pub. Date : 2017 Jan 2

PMID : 27870396






1 Functional Relationships(s)
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1 Preclinical models have demonstrated increased sensitivity of females to CRF and noradrenergic-induced drug reinstatement compared with males, and, consistent with these findings, human laboratory studies have demonstrated greater sensitivity to corticotropin-releasing hormone (CRH) and noradrenergic stimulation in cocaine-dependent women compared with men. Cocaine corticotropin releasing hormone Homo sapiens