Title : The anti-hyperplasia, anti-oxidative and anti-inflammatory properties of Qing Ye Dan and swertiamarin in testosterone-induced benign prostatic hyperplasia in rats.

Pub. Date : 2017 Jan 4

PMID : 27866977






1 Functional Relationships(s)
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1 It showed that QYD and swertiamarin ameliorated the testosterone-induced prostatic hyperplasia and collagen deposition, attenuated the over-expressions of HIF-1alpha, VEGF, EGF, betaFGF, PCNA, AR and ER-alpha, reduced the ratio of Bcl-2/Bax, enhanced the expression of ER-beta, inhibited the oxidative stress and local inflammation, as well as relieved prostatic EMT. Testosterone androgen receptor Rattus norvegicus