Title : Amyloid-β Peptide Nitrotyrosination Stabilizes Oligomers and Enhances NMDAR-Mediated Toxicity.

Pub. Date : 2016 Nov 16

PMID : 27852777






2 Functional Relationships(s)
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1 SIGNIFICANCE STATEMENT: We report that nitration (i.e., the irreversible addition of a nitro group) of the Alzheimer-related peptide amyloid-beta (Abeta) favors the stabilization of highly toxic oligomers and inhibits the formation of Abeta fibrils. nitro amyloid beta (A4) precursor protein Mus musculus
2 SIGNIFICANCE STATEMENT: We report that nitration (i.e., the irreversible addition of a nitro group) of the Alzheimer-related peptide amyloid-beta (Abeta) favors the stabilization of highly toxic oligomers and inhibits the formation of Abeta fibrils. nitro amyloid beta (A4) precursor protein Mus musculus