Pub. Date : 2017 Feb
PMID : 27842238
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Classical modes of NLRP3 activation entail a priming step that enables its activation (signal 1) and a potassium efflux-dependent activation signal (signal 2) that triggers pyroptosome formation and pyroptosis, a lytic cell death necessary for IL-1beta release. | Potassium | NLR family pyrin domain containing 3 | Homo sapiens |