Title : Co-expression of the recombined alcohol dehydrogenase and glucose dehydrogenase and cross-linked enzyme aggregates stabilization.

Pub. Date : 2017 Jan

PMID : 27838320






1 Functional Relationships(s)
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1 As the key chiral precursor of Crizotinib (S)-1-(2,6-dichloro-3-fluorophenyl) phenethyl alcohol can be prepared from 1-(2,6-dichloro-3-fluorophenyl) acetophenone by the reductive coupling reactions of alcohol dehydrogenase (ADH) and glucose dehydrogenases (GDH). (s)-1-(2,6-dichloro-3-fluorophenyl) phenethyl alcohol Alcohol dehydrogenase Escherichia coli