Title : Autophagy Prevents Oxidative Stress-Induced Loss of Self-Renewal Capacity and Stemness in Human Tendon Stem Cells by Reducing ROS Accumulation.

Pub. Date : 2016

PMID : 27832632






1 Functional Relationships(s)
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1 Pretreatment with starvation or rapamycin prior to H2O2 exposure also led to decreased intracellular and mitochondrial ROS accumulation along with increased autophagic activity, as manifested in increased LC3 cleavage, Beclin-1 expression, and GFP-LC3-labeled autophagosome formation. Hydrogen Peroxide microtubule associated protein 1 light chain 3 alpha Homo sapiens