Title : MPTP Impairs Dopamine D1 Receptor-Mediated Survival of Newborn Neurons in Ventral Hippocampus to Cause Depressive-Like Behaviors in Adult Mice.

Pub. Date : 2016

PMID : 27790091






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Protein kinase A (PKA) and Ca2+/cAMP-response element binding protein (CREB) phosphorylation were reduced in v-DG of MPTP-mice, which were reversed by D1-like receptor (D1R) agonist SKF38393, but not D2R agonist quinpirole. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine cAMP responsive element binding protein 1 Mus musculus
2 Protein kinase A (PKA) and Ca2+/cAMP-response element binding protein (CREB) phosphorylation were reduced in v-DG of MPTP-mice, which were reversed by D1-like receptor (D1R) agonist SKF38393, but not D2R agonist quinpirole. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine cAMP responsive element binding protein 1 Mus musculus