Title : Prevention and antagonism of acute carbofuran intoxication by memantine and atropine.

Pub. Date : 1989

PMID : 2778846






1 Functional Relationships(s)
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1 A single sc dose of memantine HCl (MEM, 18 mg/kg) and atropine sulfate (ATS, 16 mg/kg) 60 and 15 min, respectively, prior to carbofuran administration completely prevented the expected gross toxic signs and significantly (p less than .01) attenuated the carbofuran-induced inhibition of AChE activity. Atropine acetylcholinesterase Rattus norvegicus