Title : Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors.

Pub. Date : 2016 Oct 25

PMID : 27783942






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibitor combinations targeting both receptors and the dual inhibitor ponatinib suppress the AKT and ERK1/2 pathways leading to apoptosis. ponatinib AKT serine/threonine kinase 1 Homo sapiens